Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082202 | 0.70 | PTPN1 (0.44) | PTPN1KCNK3KCNK9PRMT1NPC1 | |
| SCHEMBL7186213 | 0.69 | PTPN1 (0.40) | PTPN1KCNK3KCNK9NPC1RAB9A | |
| SCHEMBL777642 | 0.67 | PTPN1 (0.44) | PTPN1KCNK3KCNK9LMNANPC1 | |
| SCHEMBL16502305 | 0.66 | NPC1 (0.42) | PTPN1KCNK3KCNK9PRMT1LMNA | |
| SCHEMBL6154308 | 0.65 | — | — | |
| SCHEMBL6174798 | 0.65 | KMT2A (0.41) | PTPN1KCNK3KCNK9LMNAHTT | |
| SCHEMBL22305399 | 0.64 | KCNK3 (0.83) | PTPN1KCNK3KCNK9HTTNPC1 | |
| SCHEMBL11831465 | 0.62 | MEN1 (0.64) | PTPN1KCNK3KCNK9HTTNPC1 | |
| SCHEMBL370375 | 0.62 | PTPN1 (0.42) | PTPN1KCNK3KCNK9PRMT1NPC1 | |
| SCHEMBL10218967 | 0.62 | KMT2A (0.47) | PTPN1KCNK3KCNK9LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165494-B1 | HSV PRIMASE INHIBITORS | BOEHRINGER INGELHEIM CA LTD (CA) | 2003-11-05 | — | — | EP | disclosed |
| EP-1165494-A2 | HSV PRIMASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2002-01-02 | — | — | EP | disclosed |
| US-6323202-B1 | BENZAMIDE SUBSTITUTES WITH KETONE COMPOUNDS AS ENZYME INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-11-27 | — | — | US | disclosed |
| WO-2000058270-A2 | HSV PRIMASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-10-05 | — | — | WO | disclosed |