Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.48 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186223 | 1.00 | PTPN1 (0.50) | PTPN1ABCG2KRAS | |
| SCHEMBL7184733 | 0.88 | PTPN1 (0.62) | PTPN1ABCG2 | |
| SCHEMBL7184735 | 0.88 | PTPN1 (0.62) | PTPN1ABCG2 | |
| SCHEMBL7191162 | 0.87 | CA1 (0.55) | PTPN1ABCG2KRAS | |
| SCHEMBL7191161 | 0.87 | CA1 (0.55) | PTPN1ABCG2KRAS | |
| SCHEMBL7189596 | 0.86 | ABCG2 (0.49) | ABCG2KRAS | |
| SCHEMBL7189594 | 0.86 | ABCG2 (0.49) | ABCG2KRAS | |
| SCHEMBL7177462 | 0.85 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL7177465 | 0.85 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL7190743 | 0.85 | PTPN1 (0.42) | PTPN1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |