Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21470297 | 0.92 | PTGER4 (0.49) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL30114942 | 0.92 | PTGER4 (0.49) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL6018506 | 0.91 | PTGER4 (0.52) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL1626699 | 0.88 | PTGER4 (0.64) | PTGER4TP53 | |
| SCHEMBL2356746 | 0.88 | PTGER4 (0.48) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL30114929 | 0.87 | PTGER4 (0.48) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL2349107 | 0.87 | PTGER4 (0.48) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL1626450 | 0.85 | PTGER4 (0.46) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL7170969 | 0.83 | PTGER4 (0.45) | PTGER4AGTR2AGTR1TP53KMT2A | |
| SCHEMBL23844020 | 0.83 | PTGER4 (0.49) | PTGER4AGTR2AGTR1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326606-A2 | EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032422-A2 | EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |