Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131268 | 0.79 | — | — | |
| SCHEMBL1131 | 0.79 | TSHR (0.40) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL14157251 | 0.79 | TSHR (0.40) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL37123 | 0.79 | TSHR (0.40) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL25206988 | 0.76 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| Water SCHEMBL37215 | 0.76 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL10851813 | 0.76 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| Water SCHEMBL28850770 | 0.76 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL9745276 | 0.76 | — | — | |
| SCHEMBL28844352 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649557-B1 | Containing acyloxy or alkoxy functionality; storage stable, fast acting; polysiloxanes, polyurethanes; paints | RHODIA CHIMIE (FR) | 2003-11-18 | — | — | US | disclosed |
| EP-0743879-B1 | USE OF TIN DERIVATIVES AS LATENT POLYCONDENSATION CATALYSTS AND PREMIXTURES CONTAINING SAME | RHODIA CHIMIE SA (FR) | 2001-07-11 | — | — | EP | disclosed |
| US-6187711-B1 | CYCLIC TIN DERIVATIVES WHICH HAVE AT LEAST ONE TIN-TIN BOND | RHODIA CHIMIE (FR) | 2001-02-13 | — | — | US | disclosed |
| EP-0743879-A1 | USE OF TIN DERIVATIVES AS LATENT POLYCONDENSATION CATALYSTS AND PREMIXTURES CONTAINING SAME | RHONE-POULENC CHIMIE (FR) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021694-A1 | USE OF TIN DERIVATIVES AS LATENT POLYCONDENSATION CATALYSTS AND PREMIXTURES CONTAINING SAME | RHONE-POULENC CHIMIE (FR) | 1995-08-17 | — | — | WO | disclosed |