Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189979 | 0.93 | ESR1 (0.51) | ESR1ESR2MEN1KMT2ACA12 | |
| SCHEMBL7187504 | 0.92 | CA12 (0.56) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL7184090 | 0.91 | CYP3A4 (0.52) | ESR1ESR2MEN1KMT2ACA12 | |
| SCHEMBL7185785 | 0.91 | CYP1A2 (0.52) | ESR1ESR2ABCG2MEN1KMT2A | |
| SCHEMBL7186129 | 0.86 | ESR1 (0.61) | ESR1ESR2ABCG2CYP3A4KDM4E | |
| SCHEMBL7186132 | 0.86 | ESR1 (0.61) | ESR1ESR2ABCG2CYP3A4KDM4E | |
| SCHEMBL7193829 | 0.85 | ESR1 (0.52) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL7192245 | 0.85 | CYP3A4 (0.48) | ESR1ESR2ABCG2MEN1KMT2A | |
| SCHEMBL7194195 | 0.85 | ESR1 (0.49) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL7195408 | 0.85 | ESR1 (0.51) | ESR1ESR2ABCG2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |