Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748200 | 0.98 | MAPT (0.70) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL3591227 | 0.89 | MAPT (0.69) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL28776951 | 0.88 | MAPT (0.68) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL2136152 | 0.86 | EGFR (0.60) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL29693710 | 0.84 | KDM4E (1.00) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL7192101 | 0.84 | KDM4E (1.00) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL8374081 | 0.83 | KDM4E (0.76) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL1549967 | 0.83 | KDM4E (0.76) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL5756441 | 0.83 | MAPT (0.61) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL12470723 | 0.83 | GAA (0.68) | MAPTKDM4ERAB9ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707297-A | Removable guidepath for automated guidance vehicles | BELL & HOWELL COMPANY (US) | 1987-11-17 | — | — | US | claimed |
| US-6582684-B1 | A fluorescent and/or phosphorescent coating composition, particularly useful as a body coating, hair coating, lipstick and particularly as a phosphorescent nail polish that has the capability of changing from transparent, or other color, in | XSIGHT INTERNATIONAL | 2003-06-24 | — | — | US | disclosed |
| US-5896297-A | Robotube delivery system | VALERINO SR FRED M (US) | 1999-04-20 | — | — | US | disclosed |
| US-4707297-A | Removable guidepath for automated guidance vehicles | BELL & HOWELL COMPANY (US) | 1987-11-17 | — | — | US | disclosed |