Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL1435191 | 0.88 | — | — | |
| SCHEMBL2734640 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL50103 | 0.87 | — | — | |
| SCHEMBL10980008 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL10979286 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL10979826 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL10984171 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL2850605 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL10982778 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL10984759 | 0.87 | TSHR (0.44) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043981-B1 | FAT-BINDING POLYMERS COMBINED WITH LIPASE INHIBITORS FOR THE TREATMENT OF OBESITY | GELTEX PHARMA INC (US) | 2003-04-16 | — | — | EP | disclosed |