Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433932 | 0.83 | AKR1C1 (0.41) | AKR1C1CYP19A1CYP11B2CYP2D6ALDH1A1 | |
| SCHEMBL28912798 | 0.80 | AKR1C1 (0.45) | AKR1C1CYP19A1CYP11B2CYP2D6ALDH1A1 | |
| SCHEMBL14946406 | 0.80 | AKR1C1 (0.45) | AKR1C1CYP19A1CYP11B2CYP2D6ALDH1A1 | |
| SCHEMBL7187433 | 0.79 | AKR1C1 (0.44) | AKR1C1CYP19A1CYP11B2CYP2D6ALDH1A1 | |
| SCHEMBL9018469 | 0.77 | AKR1C1 (0.42) | AKR1C1CYP19A1CYP11B2ALDH1A1TSHR | |
| SCHEMBL6882975 | 0.76 | AKR1C1 (0.48) | AKR1C1CYP19A1CYP11B2CYP2D6ALDH1A1 | |
| SCHEMBL7187274 | 0.74 | AKR1C1 (0.47) | AKR1C1CYP19A1CYP11B2ALDH1A1TSHR | |
| SCHEMBL16134326 | 0.72 | AKR1C1 (0.45) | AKR1C1CYP19A1CYP11B2ALDH1A1TSHR | |
| SCHEMBL9354596 | 0.72 | AKR1C1 (0.41) | AKR1C1CYP19A1CYP11B2CYP2D6ALDH1A1 | |
| SCHEMBL9354606 | 0.72 | AKR1C1 (0.41) | AKR1C1CYP19A1CYP11B2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276807-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | Dow Corning Corporation (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001083608-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |