SCHEMBL718878

SCHEMBL718878

CCCCCN1c2ccccc2Sc2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.69
KDM1A O60341 12/20 0.67
SIGMAR1 Q99720 3/20 0.65
SLC22A1 O15245 1/20 0.65
PRNP P04156 1/20 0.65
TP53 P04637 1/20 0.65
CYP1A2 P05177 1/20 0.65
ADRB2 P07550 1/20 0.65
CHRM2 P08172 1/20 0.65
CHRM4 P08173 1/20 0.65
HTR1A P08908 1/20 0.65
CHRM5 P08912 1/20 0.65
ADRA2A P08913 1/20 0.65
CYP2D6 P10635 1/20 0.65
CHRM1 P11229 1/20 0.65
DRD2 P14416 1/20 0.65
TSHR P16473 1/20 0.65
ADRA2B P18089 1/20 0.65
ADRA2C P18825 1/20 0.65
CHRM3 P20309 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31302971 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL28347553 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL29557345 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL6120214 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL342329 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL4192605 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL2784918 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL7397164 0.98 PIM1 (0.67) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL31302974 0.94 KDM1A (0.73) PIM1KDM1ASIGMAR1SLC22A1PRNP
SCHEMBL7998997 0.94 KDM1A (0.73) PIM1KDM1ASIGMAR1SLC22A1PRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232089-A Vinylphenol thiazine fluorescent probe and preparation method and application thereof 洛阳师范学院 2022-10-25 CN claimed
CN-110407830-B Method for synthesizing N-arylphenothiazine compound 河南师范大学 2020-08-04 CN claimed
EP-0827230-B1 Non-aqueous lithium ion secondary battery UBE INDUSTRIES (JP) 2006-11-22 EP claimed
US-5976731-A AMINE COMPOUND AS ELECTROLYTE FUJI PHOTO FILM CO., LTD. (JP) 1999-11-02 US claimed
EP-0827230-A2 Non-aqueous lithium ion secondary battery FUJI PHOTO FILM CO., LTD. (JP) 1998-03-04 EP claimed
US-5109134-A PROCESS FOR THE DIRECT AND REGIOSELECTIVE FUNCTIONALIZATION IN POSITION 2 OF PHENOTHIAZINE ZAMBON GROUP S.P.A. (IT) 1992-04-28 US claimed
EP-0433841-A2 Process for the direct and regioselective functionalization in position 2 of phenotiazine ZAMBON GROUP S.p.A. (IT) 1991-06-26 EP claimed
JP-4208270-A None JP disclosed
CN-115232089-A Vinylphenol thiazine fluorescent probe and preparation method and application thereof 洛阳师范学院 2022-10-25 CN disclosed
CN-110407830-B Method for synthesizing N-arylphenothiazine compound 河南师范大学 2020-08-04 CN disclosed
CN-110407830-B Method for synthesizing N-arylphenothiazine compound 河南师范大学 2020-08-04 CN disclosed
CN-110407830-B Method for synthesizing N-arylphenothiazine compound 河南师范大学 2020-08-04 CN disclosed
US-10393724-B2 Rapid identification of brake fluid GM Global Technology Operations LLC (US) 2019-08-27 US disclosed
US-4118328-A FROM A TRIARYL PHOSPHATE AND AN ALIPHATIC SECONDARY OR PRIMARY AMINE WITH BORIC ACID CATALYST; LUBRICATING OIL ADDITIVES CHEVRON RESEARCH COMPANY (US) 1978-10-03 US disclosed
US-4118329-A FROM A TRIARYL PHOSPHATE AND AN ALIPHATIC SECONDARY OR PRIMARY AMINE WITH A TRIALKYL BORATE CATALYST; LUBRICATING OIL ADDITIVES CHEVRON RESEARCH COMPANY (US) 1978-10-03 US disclosed
US-4100080-A HYDRATED POTASSIUM BORATE CHEVRON RESEARCH COMPANY (US) 1978-07-11 US disclosed
US-4100081-A POTASSIUM OR SODIUM TRIBORATE CHEVRON RESEARCH COMPANY (US) 1978-07-11 US disclosed
US-3983041-A ALKALINE EARTH CARBONATE OR CARBOXYLATE, ALKYLPHENOL-FORMALDEHYDE-AMINE MANNICH BASE CHEVRON RESEARCH COMPANY (US) 1976-09-28 US disclosed
US-3968157-A ANTIWEAR CHEVRON RESEARCH COMPANY (US) 1976-07-06 US disclosed
US-3954918-A WEAR RESISTANCE, OIL ADDITIVES CHEVRON RESEARCH COMPANY (US) 1976-05-04 US disclosed