Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189223 | 1.00 | ESR1 (0.55) | ESR1ESR2THRBATM | |
| SCHEMBL7195203 | 0.94 | ESR1 (0.58) | ESR1ESR2THRBATM | |
| SCHEMBL7195206 | 0.94 | ESR1 (0.58) | ESR1ESR2THRBATM | |
| SCHEMBL7182557 | 0.94 | ESR1 (0.59) | ESR1ESR2THRBATM | |
| SCHEMBL7182553 | 0.94 | ESR1 (0.59) | ESR1ESR2THRBATM | |
| SCHEMBL7190349 | 0.92 | ESR1 (0.52) | ESR1ESR2THRBATM | |
| SCHEMBL7190347 | 0.92 | ESR1 (0.52) | ESR1ESR2THRBATM | |
| SCHEMBL7190018 | 0.92 | ESR1 (0.56) | ESR1ESR2THRBATM | |
| SCHEMBL7190025 | 0.92 | ESR1 (0.56) | ESR1ESR2THRBATM | |
| SCHEMBL7184758 | 0.90 | ESR1 (0.58) | ESR1ESR2THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | claimed |
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | disclosed |
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |