Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183995 | 0.90 | PTPN1 (0.66) | PTPN1 | |
| SCHEMBL7183998 | 0.90 | PTPN1 (0.66) | PTPN1 | |
| SCHEMBL7186587 | 0.88 | PTPN1 (0.78) | PTPN1 | |
| SCHEMBL7186591 | 0.88 | PTPN1 (0.78) | PTPN1 | |
| SCHEMBL7188015 | 0.86 | PTPN1 (0.68) | PTPN1 | |
| SCHEMBL7188020 | 0.86 | PTPN1 (0.68) | PTPN1 | |
| SCHEMBL7190834 | 0.82 | PTPN1 (0.55) | PTPN1 | |
| SCHEMBL7190836 | 0.82 | PTPN1 (0.55) | PTPN1 | |
| SCHEMBL7177704 | 0.81 | PTPN1 (0.66) | PTPN1 | |
| SCHEMBL7177700 | 0.81 | PTPN1 (0.66) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |