SCHEMBL718942

SCHEMBL718942

C=CCCCC[Si](C)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1229831 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6037408 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL959298 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6037441 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6037409 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1230177 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1228272 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8510858 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL964644 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6037312 0.98 TSHR (0.44) TSHRALDH1A1LMNALPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2691464-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MAT INC (US) 2019-01-09 EP claimed
US-8859674-B2 Moisture curable silylated polymer compositions with improved adhesion to concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-14 US claimed
EP-2691464-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE Momentive Performance Materials Inc. (US) 2014-02-05 EP claimed
US-20120251832-A1 Moisture Curable Silylated Polymer Compositions With Improved Adhesion to Concrete MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-10-04 US claimed
WO-2012135443-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-10-04 WO claimed
EP-0863146-B1 Method of making organosilicon carbonyl compounds DOW CORNING (US) 2003-02-19 EP claimed
US-6126777-A AN AQUEOUS ADHESIVE USEFUL FOR BONDING VULCANIZABLE ELASTOMERIC RUBBER TO A SUBSTRATE, MADE FROM ALTEST ONE VINYL GROUP CONTAINING SILANE COMPOUND AND A POLYISOCYANATE; VULCANIZABLE; CURING; INCREASED SHELF-LIFE LORD CORPORATION (US) 2000-10-03 US claimed
US-5880304-A Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1999-03-09 US claimed
EP-0863146-A2 Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1998-09-09 EP claimed
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
US-12045007-B2 Toner additives comprising composite particles CABOT CORPORATION (US) 2024-07-23 US disclosed
CN-115348990-B Composition for liquid-based additive manufacturing 卡博特公司 2024-06-04 CN disclosed
CN-117777543-A Composition for liquid-based additive manufacturing 卡博特公司 2024-03-29 CN disclosed
US-20230100957-A1 Composition for Liquid-Based Additive Manufacturing CABOT CORPORATION 2023-03-30 US disclosed
EP-0691363-A1 Polystyrene modified with a telechelic polyorganosiloxane DOW CORNING CORPORATION (US) 1996-01-10 EP disclosed
EP-0690101-A2 Functional polyorganosiloxane emulsions from silanes having two hydrolysable functional groups and photocurable compositions therefrom DOW CORNING CORPORATION (US) 1996-01-03 EP disclosed
US-5449716-A Curable composition of silane and polysiloxanes with catalyst DOW CORNING CORPORATION (US) 1995-09-12 US disclosed
EP-0280423-B1 HEAT ACTIVATED SILICON-BASED ADHESIVE LORD CORPORATION (US) 1992-08-12 EP disclosed
EP-0280423-A2 Heat activated silicon-based adhesive LORD CORPORATION (US) 1988-08-31 EP disclosed
US-4690966-A BLEND OF OLEFINIC ORGANOSILANE, WATER AND ALUMINO ZIRCONIUM COMPLEX LORD CORPORATION (US) 1987-09-01 US disclosed