SCHEMBL7189525

SCHEMBL7189525

CC(C(=O)O)=C(C#N)C#N

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27172602 0.79 TSHR (0.35) TDP1
SCHEMBL11219385 0.78
SCHEMBL2580191 0.77
SCHEMBL289306 0.77
SCHEMBL8061690 0.77
SCHEMBL10895721 0.74 TDP1 (0.32) TDP1FFAR3LCKFYN
Water SCHEMBL29070199 0.73 FFAR3 (0.50) TDP1FFAR3LCKFYN
Bicarbonate SCHEMBL5085264 0.70 CA1 (0.42)
SCHEMBL10661655 0.69 FFAR3 (0.55) TDP1FFAR3LCKFYN
SCHEMBL105998 0.69 FFAR3 (0.55) TDP1FFAR3LCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025016393-A1 4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-6-ONE DERIVATIVE AND USE THEREOF IN MEDICINE 海思科医药集团股份有限公司 2025-01-23 WO disclosed
WO-2017197555-A1 FUSED PYRAZINE DERIVATIVES USEFUL AS SOLUBLE GUANYLATE CYCLASE STIMULATORS MERCK SHARP & DOHME CORP. (US) 2017-11-23 WO disclosed
WO-2017107052-A1 SOLUBLE GUANYLATE CYCLASE STIMULATORS MERCK SHARP & DOHME CORP. (US) 2017-06-29 WO disclosed
US-6562181-B2 Bonding together two substrates by applying to a first substrate formulation of mixture of trifunctional olefinic monomer, olefinic second monomer that is copolymerizable and free radical initiator; contacting second substrate LORD CORPORATION 2003-05-13 US disclosed
US-20020129896-A1 REACTIVE ADHESIVES AND COATINGS WITH TRIFUNCTIONAL OLEFINIC MONOMERS LORD CORPORATION 2002-09-19 US disclosed
EP-1190007-A2 REACTIVE ADHESIVES AND COATINGS WITH TRIFUNCTIONAL OLEFINIC MONOMERS Lord Corporation (US) 2002-03-27 EP disclosed
WO-2000077079-A2 REACTIVE ADHESIVES AND COATINGS WITH TRIFUNCTIONAL OLEFINIC MONOMERS LORD CORPORATION (US) 2000-12-21 WO disclosed