SCHEMBL7189552

SCHEMBL7189552

COc1cc(-c2ccc(CC3C(=O)N(CCCCc4ccccc4)[C@@H](C)C(=O)N3C)cc2)cc(OC)c1OC

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FSHR P23945 19/20 0.78
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141026 1.00 FSHR (0.78) FSHRMAPT
SCHEMBL6141131 0.99 FSHR (0.79) FSHR
SCHEMBL6140294 0.99 FSHR (0.79) FSHR
SCHEMBL6140268 0.99 FSHR (0.79) FSHR
SCHEMBL6140651 0.99 FSHR (0.79) FSHR
SCHEMBL6140577 0.97 FSHR (0.76) FSHRMAPT
SCHEMBL6140414 0.93 FSHR (0.72) FSHRMAPT
SCHEMBL6140451 0.93 FSHR (0.78) FSHR
SCHEMBL6140352 0.90 FSHR (0.76) FSHR
SCHEMBL6140399 0.87 FSHR (1.00) FSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1351941-A1 BISARYL DERIVATIVES HAVING FSH RECEPTOR MODULATORY ACTIVITY PHARMACOPEIA, INC. (US) 2003-10-15 EP disclosed
WO-2002070493-A1 BISARYL DERIVATIVES HAVING FSH RECEPTOR MODULATORY ACTIVITY PHARMACOPEIA, INC. (US) 2002-09-12 WO disclosed