SCHEMBL719040

SCHEMBL719040

Nc1ccc(Sc2ccc(O)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.74
NR1H2 P55055 1/20 0.74
TSHR P16473 1/20 0.74
MAPK1 P28482 1/20 0.74
ALDH1A1 P00352 3/20 0.68
CA3 P07451 2/20 0.68
ALOX15 P16050 2/20 0.68
HIF1A Q16665 2/20 0.68
HSD17B10 Q99714 2/20 0.68
CA14 Q9ULX7 2/20 0.68
THRB P10828 1/20 0.68
CA6 P23280 1/20 0.68
CASP1 P29466 1/20 0.68
APP P05067 3/20 0.52
MAPT P10636 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ESR1 P03372 2/20 0.45
CYP19A1 P11511 2/20 0.45
ESR2 Q92731 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL4163230 0.88 CYP3A4 (0.59) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL10914949 0.86 NR1H2 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL29726 0.86 NR1H2 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL9485438 0.86 CYP3A4 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL9485453 0.86 CYP3A4 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL9647870 0.86 CYP3A4 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
4,4'-Thiodianiline SCHEMBL49068 0.86 CYP3A4 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL9649030 0.86 CYP3A4 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL10813732 0.86 CYP3A4 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1
SCHEMBL9649049 0.86 CYP3A4 (1.00) CYP3A4NR1H2TSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117969623-A Novel coronavirus detection electrode based on molecularly imprinted polymer and preparation method thereof 中芯维康医疗科技(重庆)有限责任公司 2024-05-03 CN claimed
US-4737398-A POLYAZOMETHYNE, POLYESTER OR POLYCARBONATE POLYPLASTICS CO., LTD. (JP) 1988-04-12 US claimed
US-4726998-A LIQUID CRYSTAL POLYMER SUBSTRATE, MAGNETIC LAYER POLYPLASTICS CO., LTD. (JP) 1988-02-23 US claimed
US-20240191137-A1 THERMOPLASTIC COMPOSITIONS AND USES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-06-13 US disclosed
WO-2024095878-A1 MODIFIER FOR THERMOPLASTIC RESIN, RESIN COMPOSITION, USE OF HYDROGENATED AROMATIC HYDROCARBON RESIN, TACKIFIER, AND PRESSURE-SENSITIVE ADHESIVE OR ADHESIVE COMPOSITION 荒川化学工業株式会社 2024-05-10 WO disclosed
WO-2024095880-A1 MODIFYING AGENT FOR THERMOPLASTIC RESINS, RESIN COMPOSITION, AND USE OF HYDROGENATED AROMATIC HYDROCARBON RESIN 荒川化学工業株式会社 2024-05-10 WO disclosed
WO-2024095883-A1 MODIFIER FOR THERMOPLASTIC RESIN, RESIN COMPOSITION, AND USE OF ROSIN RESIN 荒川化学工業株式会社 2024-05-10 WO disclosed
CN-117969623-A Novel coronavirus detection electrode based on molecularly imprinted polymer and preparation method thereof 中芯维康医疗科技(重庆)有限责任公司 2024-05-03 CN disclosed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-115304889-A Resin composition, molded article, and fluidity improver for low dielectric resin 荒川化学工业株式会社 2022-11-08 CN disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
EP-0074700-A1 Poly(ester amide) derived from 6-hydroxy-2-naphthoic acid, another aromatic hydroxy acid, dicarboxylic acid and an aromatic monomer capable of forming an amide link CELANESE CORPORATION (US) 1983-03-23 EP disclosed
EP-0067032-A1 Poly(ester-amide) capable of forming an anisotropic melt phase derived from p-hydroxybenzoic acid, 2,6-dihydroxynaphthalene, carbocyclic dicarboxylic acid, aromatic monomer capable of forming an amide linkage and, optinally, additional aromatic diol CELANESE CORPORATION (US) 1982-12-15 EP disclosed
EP-0063881-A1 Poly(ester-amide) derived from p-hydroxybenzoic acid, 2,6-naphthalene-dicarboxylic acid and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-11-03 EP disclosed
US-4355132-A Anisotropic melt phase forming poly(ester-amide) derived from p-hydroxybenzoic acid, 2,6-naphthalenedicarboxylic acid, aromatic monomer capable of forming an amide linkage, and, optionally, hydroquinone and additional carbocyclic dicarboxylic acid CELANESE CORPORATION (US) 1982-10-19 US disclosed
US-4351918-A Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, other aromatic hydroxyacid, carbocyclic dicarboxylic acid, and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-09-28 US disclosed
US-4341688-A Poly(ester-amide) capable of forming an anisotropic melt phase derived from dihydroxyanthraquinone, hydroxybenzoic acid, dicarboxylic acid, and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-07-27 US disclosed
US-4339375-A Poly(ester-amide) capable of forming an anisotropic melt phase derived from p-hydroxybenzoic acid, 2,6-dihydroxynaphthalene, carbocyclic dicarboxylic acid, aromatic monomer capable of forming an amide linkage, and, optionally, additional aromatic diol CELANESE CORPORATION (US) 1982-07-13 US disclosed
EP-0053940-A1 Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, dicarboxylic acid and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-06-16 EP disclosed
US-4330457-A Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, dicarboxylic acid, and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-05-18 US disclosed