⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21894263 | 0.65 | — | — | |
| SCHEMBL31710606 | 0.60 | — | — | |
| SCHEMBL6279388 | 0.59 | — | — | |
| SCHEMBL31685305 | 0.57 | ADORA2A (0.52) | — | |
| SCHEMBL9312042 | 0.55 | DAO (0.35) | — | |
| SCHEMBL23948971 | 0.54 | — | — | |
| SCHEMBL8404471 | 0.54 | — | — | |
| SCHEMBL1357553 | 0.53 | — | — | |
| SCHEMBL1042322 | 0.51 | — | — | |
| SCHEMBL4110758 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868173-A | CONTAIN AMINE SALT GROUP | ICI PHARMA (FR) | 1989-09-19 | — | — | US | claimed |
| EP-0182633-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1986-05-28 | — | — | EP | claimed |
| US-6566355-B1 | Useful in combination with beta -lactam antibiotics in the control of beta -lactamase forming pathogens | HOFFMANN-LA ROCHE INC. | 2003-05-20 | — | — | US | disclosed |
| US-5698577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5510343-A | BETA-LACTAMASE INHIBITOR | HOFFMANN-LA ROCHE INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-4680408-A | SELENAZOLES, CEPHALOSPORIN DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1987-07-14 | — | — | US | disclosed |
| US-4593093-A | Containing a (oxa)cephem structure | HOFFMANN-LA ROCHE INC. (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0182633-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1986-05-28 | — | — | EP | disclosed |
| US-4458072-A | CEPHALOSPORIN AND OXACEPHALOSPORIN BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1984-07-03 | — | — | US | disclosed |