Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179792 | 0.95 | ABCG2 (0.42) | ABCG2CYP1A1CYP1B1DPP4MAPT | |
| SCHEMBL7182728 | 0.90 | PTPN1 (0.40) | ABCG2CYP1A1CYP1B1DPP4MAPT | |
| SCHEMBL7185108 | 0.89 | CYP1A1 (0.42) | ABCG2CYP1A1CYP1B1MAPTALDH1A1 | |
| SCHEMBL7185112 | 0.89 | CYP1A1 (0.42) | ABCG2CYP1A1CYP1B1MAPTALDH1A1 | |
| SCHEMBL7796250 | 0.88 | ABCG2 (0.53) | ABCG2CYP1A1CYP1B1DPP4MAPT | |
| SCHEMBL7189584 | 0.87 | CA1 (0.42) | ABCG2CYP1A1CYP1B1DPP4MAPT | |
| SCHEMBL7184017 | 0.87 | ABCG2 (0.43) | ABCG2CYP1A1CYP1B1DPP4MAPT | |
| SCHEMBL7191537 | 0.85 | ABCG2 (0.40) | ABCG2CYP1A1CYP1B1DPP4MAPT | |
| SCHEMBL7185258 | 0.85 | PTPN1 (0.41) | ABCG2CYP1A1CYP1B1DPP4ABCC1 | |
| SCHEMBL7192274 | 0.84 | ABCG2 (0.42) | ABCG2CYP1A1CYP1B1DPP4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |