Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | INHA | P05111 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26092780 | 0.91 | EP300 (0.42) | CYP19A1TSHRALDH1A1TRPV1PPARG | |
| SCHEMBL10457056 | 0.91 | EP300 (0.42) | CYP19A1TSHRALDH1A1TRPV1PPARG | |
| SCHEMBL957232 | 0.78 | — | — | |
| SCHEMBL57502 | 0.78 | — | — | |
| SCHEMBL7278067 | 0.78 | PPARG (0.44) | CYP19A1TSHRALDH1A1CNR1TRPV1 | |
| SCHEMBL11855184 | 0.78 | TSHR (0.47) | TSHRALDH1A1TRPV1F7F3 | |
| SCHEMBL15487091 | 0.78 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL23044056 | 0.78 | KMT2A (0.47) | ALDH1A1CNR1CNR2TRPV1TRPA1 | |
| SCHEMBL6201373 | 0.76 | TSHR (0.39) | TSHRALDH1A1KMT2AALOX15 | |
| SCHEMBL3492594 | 0.74 | KMT2A (0.36) | TSHRALDH1A1KMT2ASQLEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874001-B1 | Hydrosilated crystalline high trans polybutadiene with silica filler, tires having a base of said composition and method of preparing same | BRIDGESTONE CORP (JP) | 2003-02-05 | — | — | EP | disclosed |
| US-6017985-A | A RUBBER ADDITIVE OF SILANE DERIVATIVE OF THE HIGH TRANS-1,4 POLYBUTADIENE CAN BE BLENDED WITH RUBBERS AND SILICA FILLERS TO PROVIDE REDUCED MOONEY VISCOSITY AND LOWER HYSTERESIS PROPERTIES | BRIDGESTONE CORPORATION (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0874001-A1 | Hydrosilated crystalline high trans polybutadiene with silica filler, tires having a base of said composition and method of preparing same | Bridgestone Corporation (JP) | 1998-10-28 | — | — | EP | disclosed |