Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192165 | 1.00 | ABCG2 (0.47) | ABCG2PTPN1CAPN1DPP4PDE4A | |
| SCHEMBL7178869 | 0.87 | ABCG2 (0.48) | ABCG2PTPN1CAPN1DPP4PDE4A | |
| SCHEMBL7178873 | 0.87 | ABCG2 (0.48) | ABCG2PTPN1CAPN1DPP4PDE4A | |
| SCHEMBL7177542 | 0.84 | ABCG2 (0.45) | ABCG2PTPN1CAPN1DPP4PDE4A | |
| SCHEMBL7177538 | 0.84 | ABCG2 (0.45) | ABCG2PTPN1CAPN1DPP4PDE4A | |
| SCHEMBL7177356 | 0.84 | ABCG2 (0.44) | ABCG2PTPN1CAPN1PDE4APDE4B | |
| SCHEMBL7185712 | 0.83 | TNFRSF1A (0.54) | ABCG2PTPN1TNFRSF1ACTSLCTSB | |
| SCHEMBL7185707 | 0.83 | TNFRSF1A (0.54) | ABCG2PTPN1TNFRSF1ACTSLCTSB | |
| SCHEMBL7182953 | 0.82 | ABCG2 (0.45) | ABCG2PTPN1CAPN1PDE4APDE4B | |
| SCHEMBL7185054 | 0.82 | PTPN1 (0.47) | ABCG2PTPN1CAPN1DPP4PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |