Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13336792 | 0.89 | FGFR3 (0.88) | FGFR3KDR | |
| Hydrochloric Acid SCHEMBL3323791 | 0.88 | FGFR3 (0.86) | FGFR3KDR | |
| SCHEMBL13336859 | 0.87 | KDR (0.81) | FGFR3KDR | |
| SCHEMBL11908174 | 0.87 | FGFR3 (1.00) | FGFR3KDR | |
| SCHEMBL13062801 | 0.87 | FGFR3 (0.82) | FGFR3KDR | |
| SCHEMBL557675 | 0.87 | FGFR3 (0.79) | FGFR3KDR | |
| SCHEMBL3324062 | 0.86 | FGFR3 (0.82) | FGFR3KDR | |
| SCHEMBL557526 | 0.86 | FGFR3 (0.85) | FGFR3KDR | |
| SCHEMBL557289 | 0.86 | FGFR3 (0.83) | FGFR3KDR | |
| Hydrochloric Acid SCHEMBL3321249 | 0.86 | FGFR3 (0.80) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8131527-B1 | FGFR pharmacophore compounds | ASTEX THERAPEUTICS LTD. (GB) | 2012-03-06 | — | — | US | disclosed |
| US-8131527-B1 | FGFR pharmacophore compounds | ASTEX THERAPEUTICS LTD. (GB) | 2012-03-06 | — | — | US | disclosed |
| US-8131527-B1 | FGFR pharmacophore compounds | ASTEX THERAPEUTICS LTD. (GB) | 2012-03-06 | — | — | US | disclosed |