Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 13/20 | 0.56 |
| ▸ | ESR1 | P03372 | 9/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933964 | 1.00 | ESR2 (0.56) | ESR2ESR1SHBGKDM4EGAA | |
| SCHEMBL11766670 | 0.75 | MAPT (0.59) | KDM4EALDH1A1SMN1; SMN2CA12CA9 | |
| SCHEMBL11766676 | 0.75 | MAPT (0.59) | KDM4EALDH1A1SMN1; SMN2CA12CA9 | |
| SCHEMBL6931580 | 0.73 | NQO1 (0.54) | ESR2ESR1KDM4EGAAALDH1A1 | |
| SCHEMBL6825266 | 0.72 | ESR2 (1.00) | ESR2ESR1SHBGKDM4EGAA | |
| SCHEMBL9642463 | 0.72 | MAPT (0.60) | KDM4EGAAALDH1A1CA12TNF | |
| SCHEMBL9642459 | 0.72 | MAPT (0.60) | KDM4EGAAALDH1A1CA12TNF | |
| SCHEMBL3766383 | 0.71 | KDM4E (0.74) | ESR2ESR1SHBGKDM4EGAA | |
| SCHEMBL15413701 | 0.71 | ESR2 (0.62) | ESR2ESR1KDM4EGAAALDH1A1 | |
| SCHEMBL18073978 | 0.71 | ESR2 (0.63) | ESR2ESR1SHBGKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1213055-C | Novel ribose-substituted aromatic amides, method for prodn. and use thereof as medicaments | AVENTIS PHARMA SA (FR) | 2005-08-03 | — | — | CN | disclosed |
| US-6579902-B1 | Antibiotic; ethoxy-carbamic acid 3'-ester of N-(7-((6-deoxy-5-C-methyl-4-O- methyl-alpha-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1 -benzopyran-3-yl)-benzeneacetamide | AVENTIS PHARMA S.A. (FR) | 2003-06-17 | — | — | US | disclosed |
| EP-1173455-A2 | NOVEL RIBOSE-SUBSTITUTED AROMATIC AMIDES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Aventis Pharma S.A. (FR) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063222-A2 | NOVEL RIBOSE-SUBSTITUTED AROMATIC AMIDES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA S.A. (FR) | 2000-10-26 | — | — | WO | disclosed |