SCHEMBL7195046

SCHEMBL7195046

Clc1cccc(Sc2cccc(Sc3ccccc3)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
SLC6A2 P23975 1/20 0.49
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
ALDH1A1 P00352 1/20 0.47
RHEB Q15382 1/20 0.46
HTR2C P28335 2/20 0.46
HTR6 P50406 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
PKM P14618 1/20 0.45
GRM5 P41594 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3282084 0.98 POLB (0.56) POLBSLC6A2SLC6A4SLC6A3LMNA
SCHEMBL10596007 0.93 POLB (0.55) POLBSLC6A2SLC6A4SLC6A3LMNA
SCHEMBL10708413 0.91 POLB (0.62) POLBSLC6A2SLC6A4SLC6A3LMNA
SCHEMBL2282611 0.91 POLB (0.56) POLBSLC6A2SLC6A4SLC6A3LMNA
SCHEMBL29543630 0.91 POLB (0.56) POLBSLC6A2SLC6A4SLC6A3LMNA
SCHEMBL30688805 0.91 POLB (0.56) POLBSLC6A2SLC6A4SLC6A3LMNA
SCHEMBL11816219 0.86 POLB (0.59) POLBSLC6A2SLC6A4SLC6A3MEN1
SCHEMBL3785704 0.86 CHRNA7 (0.46) POLBLMNAHPGDALDH1A1HTR2C
SCHEMBL9557022 0.85 HTR2C (0.56) SLC6A4KDM4EHPGDALDH1A1HTR2C
SCHEMBL3889754 0.85 HTR2C (0.56) SLC6A4KDM4EHPGDALDH1A1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed