Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL7195075

Clc1ccc(-c2ccccc2)cc1.Clc1ccc(-c2ccccc2)cc1.S

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.94
TSHR P16473 1/20 0.59
ALDH1A1 P00352 4/20 0.56
LMNA P02545 2/20 0.56
KDM4E B2RXH2 2/20 0.56
GAA P10253 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CYP2A6 P11509 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 1/20 0.48
HTT P42858 1/20 0.48
CTRC Q99895 1/20 0.48
MAP4K4 O95819 1/20 0.48
AHR P35869 1/20 0.48
MAPK1 P28482 1/20 0.48
CYP3A4 P08684 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MMP3 P08254 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454036 0.97 CYP1A2 (1.00) CYP1A2TSHRALDH1A1LMNAKDM4E
SCHEMBL183912 0.97 CYP1A2 (1.00) CYP1A2TSHRALDH1A1LMNAKDM4E
Phosphine SCHEMBL5144006 0.94 CYP1A2 (0.94) CYP1A2TSHRALDH1A1LMNAKDM4E
Lithium SCHEMBL30864207 0.94 CYP1A2 (0.94) CYP1A2TSHRALDH1A1LMNAKDM4E
Water SCHEMBL10875875 0.94 CYP1A2 (0.94) CYP1A2TSHRALDH1A1LMNAKDM4E
Water SCHEMBL6336149 0.94 CYP1A2 (0.94) CYP1A2TSHRALDH1A1LMNAKDM4E
SCHEMBL29220721 0.94 CYP1A2 (0.94) CYP1A2TSHRALDH1A1LMNAKDM4E
Biphenyl SCHEMBL27859632 0.94 CYP1A2 (0.93) CYP1A2TSHRALDH1A1LMNAKDM4E
Ethylene SCHEMBL3705594 0.91 CYP1A2 (0.88) CYP1A2TSHRALDH1A1LMNAKDM4E
SCHEMBL21663932 0.88 CYP1A2 (0.83) CYP1A2TSHRALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed
EP-0778334-A1 HEAT-RESISTANT LUBRICATING OIL COMPOSITION Tonen Corporation (JP) 1997-06-11 EP disclosed