Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645251 | 0.76 | — | — | |
| SCHEMBL31226350 | 0.74 | — | — | |
| SCHEMBL11897283 | 0.74 | TSHR (0.33) | ALDH1A1CYP2C19TSHR | |
| SCHEMBL4787295 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28147609 | 0.72 | MAPT (0.32) | MAPT | |
| SCHEMBL28804648 | 0.71 | — | — | |
| SCHEMBL22618867 | 0.70 | NR1H2 (0.30) | — | |
| SCHEMBL8063876 | 0.70 | MAPT (0.31) | MAPT | |
| SCHEMBL790663 | 0.69 | — | — | |
| SCHEMBL25197739 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992474-B1 | Process for transferring alpha,beta-unsaturated alkyl groups to electrophiles | CHEMETALL GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6291713-B1 | TRANSFERRING .ALPHA.,.BETA.-UNSATURATED ALKYL GROUPS TO ELECTROPHILE BY MEANS OF MASKED ZINC ALKYL IN PRESENCE OF APROTIC SOLVENT | METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) | 2001-09-18 | — | — | US | disclosed |
| EP-0992474-A1 | Process for transferring alpha,beta-unsaturated alkyl groups to electrophiles | Metallgesellschaft Aktiengesellschaft (DE) | 2000-04-12 | — | — | EP | disclosed |