Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.72 |
| ▸ | MAPK13 | O15264 | 13/20 | 0.72 |
| ▸ | MAPK12 | P53778 | 13/20 | 0.72 |
| ▸ | MAPK11 | Q15759 | 13/20 | 0.72 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | ARNT | P27540 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907450 | 0.86 | MAPK14 (0.81) | MAPK14MAPK13MAPK12MAPK11AVPR2 | |
| SCHEMBL1907229 | 0.85 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11AVPR2 | |
| SCHEMBL6655015 | 0.84 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11EPAS1 | |
| SCHEMBL7199694 | 0.83 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11AVPR2 | |
| SCHEMBL7195732 | 0.82 | MAPK13 (0.76) | MAPK14MAPK13MAPK12MAPK11EPAS1 | |
| SCHEMBL7196766 | 0.82 | MAPK14 (0.79) | MAPK14MAPK13MAPK12MAPK11AVPR2 | |
| SCHEMBL7196772 | 0.81 | MAPK14 (0.82) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1904637 | 0.81 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11AVPR2 | |
| SCHEMBL1906421 | 0.80 | MAPK14 (0.87) | MAPK14MAPK13MAPK12MAPK11AVPR2 | |
| SCHEMBL7196619 | 0.80 | MAPK13 (0.76) | MAPK14MAPK13MAPK12MAPK11GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202954-B1 | NOVEL AMINOBENZOPHENONES | LEO PHARMA AS (DK) | 2003-10-01 | — | — | EP | disclosed |
| US-6624199-B1 | Prophylaxis and treatment of acne and acne related skin diseases with aminobenzophenones, and novel compounds effective in the treatment, as well as pharmaceutical preparations containing these compounds and dosage units | LEO PHARMACEUTICALS PRODUCTS LTD. A/S (DK) | 2003-09-23 | — | — | US | disclosed |
| EP-1202954-A1 | NOVEL AMINOBENZOPHENONES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001005744-A1 | NOVEL AMINOBENZOPHENONES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-01-25 | — | — | WO | disclosed |