Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 6/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | BCL2 | P10415 | 5/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193408 | 0.89 | PIK3C2B (0.42) | PIK3C2BPIK3CBBCL2MCL1DCTPP1 | |
| SCHEMBL7174294 | 0.89 | PIK3C2B (0.41) | PIK3C2BPIK3CBBCL2MCL1PIK3CD | |
| SCHEMBL7203763 | 0.88 | PIK3C2B (0.41) | PIK3C2BPIK3CBBCL2MCL1DCTPP1 | |
| SCHEMBL6500619 | 0.84 | PIK3C2B (0.42) | PIK3C2BPIK3CBBCL2MCL1ALOX5AP | |
| SCHEMBL7195514 | 0.84 | PIK3C2B (0.40) | PIK3C2BPIK3CBBCL2MCL1 | |
| SCHEMBL6501220 | 0.83 | BCL2 (0.40) | PIK3C2BBCL2MCL1DCTPP1PLA2G2A | |
| SCHEMBL6500552 | 0.81 | MRGPRX4 (0.49) | PIK3C2BBCL2MCL1ALOX5APPLA2G2A | |
| SCHEMBL7195498 | 0.80 | GLP1R (0.41) | PIK3C2BALOX5AP | |
| SCHEMBL7196721 | 0.80 | PPARG (0.46) | ALOX5AP | |
| SCHEMBL6501134 | 0.80 | BCL2 (0.47) | PIK3C2BPIK3CBBCL2MCL1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |