Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.36 |
| ▸ | IDH1 | O75874 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CALML3 | P27482 | 1/20 | 0.32 |
| ▸ | SDHA | P31040 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383830 | 0.91 | MAOB (0.34) | MAOBIDH1MAOALMNAPTGS1 | |
| SCHEMBL5381642 | 0.73 | CALML3 (0.54) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5383827 | 0.73 | MAOB (0.51) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL14580120 | 0.73 | MAOB (0.51) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6098143 | 0.72 | CMA1 (0.36) | MAOBIDH1MAOALMNAPTGS1 | |
| SCHEMBL14580176 | 0.69 | MAOB (0.56) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5390741 | 0.69 | MAOB (0.61) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5383717 | 0.69 | MAOB (0.52) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8257483 | 0.69 | F10 (0.41) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL14580104 | 0.69 | MAOB (0.47) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345913-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Reddy's Laboratories Ltd. (IN) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051819-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2002-07-04 | — | — | WO | disclosed |