Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 9/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6397857 | 0.85 | MAPK14 (0.69) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL7196080 | 0.85 | MAPK13 (0.63) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL7195483 | 0.84 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL7198676 | 0.83 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL7198829 | 0.83 | MAPK14 (0.79) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL7196956 | 0.83 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL6824668 | 0.82 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL6910297 | 0.81 | MAPK13 (0.49) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL7210815 | 0.81 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL6820954 | 0.80 | MAPK1 (0.48) | MAPK13MAPK12MAPK11MAPK14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202954-B1 | NOVEL AMINOBENZOPHENONES | LEO PHARMA AS (DK) | 2003-10-01 | — | — | EP | disclosed |
| US-6624199-B1 | Prophylaxis and treatment of acne and acne related skin diseases with aminobenzophenones, and novel compounds effective in the treatment, as well as pharmaceutical preparations containing these compounds and dosage units | LEO PHARMACEUTICALS PRODUCTS LTD. A/S (DK) | 2003-09-23 | — | — | US | disclosed |