Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199168 | 0.98 | PPARG (0.47) | PPARGALOX5APPTGESALOX5THRB | |
| SCHEMBL7197576 | 0.90 | PPARG (0.44) | PPARGALOX5APPTGESALOX5THRB | |
| SCHEMBL6498744 | 0.87 | PPARG (0.51) | PPARGALOX5APTHRBDCTPP1PDE2A | |
| SCHEMBL6491422 | 0.87 | PPARG (0.51) | PPARGALOX5APTHRBPDE2ATHRA | |
| SCHEMBL6492145 | 0.87 | PPARG (0.51) | PPARGALOX5APTHRBPDE2ATHRA | |
| SCHEMBL6487612 | 0.87 | PPARG (0.51) | PPARGALOX5APACSS2 | |
| SCHEMBL7194187 | 0.86 | PPARG (0.40) | PPARGALOX5APPTGESALOX5THRB | |
| SCHEMBL7194795 | 0.86 | PPARG (0.40) | PPARGPTGESALOX5THRBSMN1; SMN2 | |
| SCHEMBL6500098 | 0.86 | PPARG (0.50) | PPARGALOX5APTHRBPDE2ATHRA | |
| SCHEMBL6301607 | 0.86 | PPARG (0.58) | PPARGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |