SCHEMBL7197151

SCHEMBL7197151

O=C(O)c1ccc(N2C(=O)c3ccc(O)cc3C2=O)cc1

nearest known ligand 0.75

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.75
ESR2 Q92731 2/20 0.75
CA9 Q16790 8/20 0.70
CA12 O43570 7/20 0.70
CA1 P00915 7/20 0.70
CA2 P00918 4/20 0.68
SCN2A Q99250 1/20 0.68
CA4 P22748 3/20 0.61
MEN1 O00255 1/20 0.59
GFER P55789 1/20 0.59
KMT2A Q03164 1/20 0.59
CA7 P43166 1/20 0.59
NPSR1 Q6W5P4 1/20 0.58
PPARA Q07869 1/20 0.57
SIRT6 Q8N6T7 1/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30725842 1.00 ESR1 (0.75) ESR1ESR2CA9CA12CA1
SCHEMBL28413453 0.95 ESR1 (0.69) ESR1ESR2CA9CA12CA1
SCHEMBL8066756 0.90 ESR1 (0.70) ESR1ESR2CA9CA12CA1
SCHEMBL4234750 0.88 CA9 (0.77) CA9CA12CA1CA2SCN2A
SCHEMBL9632877 0.88 ESR1 (0.96) ESR1ESR2POLB
SCHEMBL28413804 0.87 ESR1 (0.60) ESR1ESR2CA9CA12CA1
SCHEMBL9339007 0.86 CA9 (0.77) CA9CA12CA1CA2SCN2A
Acetic Acid SCHEMBL9502886 0.86 CA9 (0.72) ESR1ESR2CA9CA12CA1
SCHEMBL5530724 0.86 ESR1 (1.00) ESR1ESR2MEN1KMT2APOLB
SCHEMBL28410207 0.84 NPSR1 (0.63) ESR1ESR2CA9CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186404-A Benzocyclobutene-containing polyester imide, thermosetting material and preparation method 江汉大学 2023-12-08 CN claimed
JP-2174759-A None JP disclosed
CN-117186404-A Benzocyclobutene-containing polyester imide, thermosetting material and preparation method 江汉大学 2023-12-08 CN disclosed
WO-2014151953-A1 COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2014-09-25 WO disclosed
US-6649680-B2 Thermoplastic resin; liquid crystal polymer; silicone compound as a flame retardant; good fluidity and excellent recycling property, can give a molded article having excellent rigidity DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-11-18 US disclosed
US-20020055563-A1 Flame retardant resin composition DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-09 US disclosed
EP-0674683-B1 POLYMERIC BLENDS RAYCHEM CORP (US) 1997-10-15 EP disclosed
EP-0674683-A1 POLYMERIC BLENDS. RAYCHEM CORP (US) 1995-10-04 EP disclosed
WO-1994014890-A1 POLYMERIC BLENDS RAYCHEM CORPORATION (US) 1994-07-07 WO disclosed
EP-0492645-A2 Fluorine-containing meltable resin composition DAIKIN INDUSTRIES, LIMITED (JP) 1992-07-01 EP disclosed
JP-H02174759-A PHTHALIMIDE COMPOUND AND PRODUCTION THEREOF JAPAN SYNTHETIC RUBBER CO LTD 1990-07-06 JP disclosed