SCHEMBL7197286

SCHEMBL7197286

Cc1ccc(-c2nc3ccccc3s2)c(O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.72
KDM4E B2RXH2 9/20 0.72
RAB9A P51151 8/20 0.72
NPC1 O15118 6/20 0.72
NPSR1 Q6W5P4 2/20 0.72
RXFP1 Q9HBX9 3/20 0.63
SMN1; SMN2 Q16637 7/20 0.58
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
GAA P10253 5/20 0.58
POLB P06746 3/20 0.58
HSD17B10 Q99714 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
APP P05067 1/20 0.58
THRB P10828 1/20 0.58
ALOX15 P16050 1/20 0.58
CASP1 P29466 1/20 0.58
SNCA P37840 1/20 0.58
CASP7 P55210 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27969672 0.98 MAPT (0.70) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL2790890 0.89 MAPT (0.69) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL27769428 0.88 MAPT (0.68) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL25329016 0.84 MAPT (0.69) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL30211740 0.84 MAPT (0.69) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL28957331 0.84 MAPT (0.55) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL29693710 0.84 KDM4E (1.00) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL7192101 0.84 KDM4E (1.00) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL1549967 0.83 KDM4E (0.76) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL8374081 0.83 KDM4E (0.76) MAPTKDM4ERAB9ANPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104610955-B A kind of Ratio-type detects the synthesis and application of fluorine ion and inferior sulfate radical fluorescent molecular probe simultaneously 中南大学 2018-10-30 CN claimed
CN-104610955-A Synthesis method and application of ratiometric fluorescent molecular probe for simultaneously detecting fluorine ion and sulfite radical UNIV CENTRAL SOUTH 2015-05-13 CN claimed
US-4707297-A Removable guidepath for automated guidance vehicles BELL & HOWELL COMPANY (US) 1987-11-17 US claimed
CN-104610955-B A kind of Ratio-type detects the synthesis and application of fluorine ion and inferior sulfate radical fluorescent molecular probe simultaneously 中南大学 2018-10-30 CN disclosed
US-9822164-B2 Labelling agent, and composition for labelling a protein, method for labelling a protein, and method for detecting a protein KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-11-21 US disclosed
US-9601704-B2 Organic light-emitting device and display apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-9466804-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2016-10-11 US disclosed
US-20160121293-A1 LABELLING AGENT, AND COMPOSITION FOR LABELLING A PROTEIN, METHOD FOR LABELLING A PROTEIN, AND METHOD FOR DETECTING A PROTEIN KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-05-05 US disclosed
US-20150364703-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150357587-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
CN-103408505-B A kind of is the method that Material synthesis 2-replaces benzo thiazole derivative with carboxylic acid and disulphide NEI MONGOL POLYTECHNICAL UNIV. (CN) 2015-11-25 CN disclosed
US-20150333279-A1 ORGANIC LIGHT-EMITTING ELEMENT AND DISPLAY APPARATUS SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-19 US disclosed
CN-104610955-A Synthesis method and application of ratiometric fluorescent molecular probe for simultaneously detecting fluorine ion and sulfite radical UNIV CENTRAL SOUTH 2015-05-13 CN disclosed
CN-103408505-A Method for synthesizing 2-substituted benzothiazole derivative by adopting carboxylic acid and disulfide as raw materials UNIV INNER MONGOLIA TECHNOLOGY 2013-11-27 CN disclosed
US-6582684-B1 A fluorescent and/or phosphorescent coating composition, particularly useful as a body coating, hair coating, lipstick and particularly as a phosphorescent nail polish that has the capability of changing from transparent, or other color, in XSIGHT INTERNATIONAL 2003-06-24 US disclosed
US-5896297-A Robotube delivery system VALERINO SR FRED M (US) 1999-04-20 US disclosed
US-4707297-A Removable guidepath for automated guidance vehicles BELL & HOWELL COMPANY (US) 1987-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160121293-A1 LABELLING AGENT, AND COMPOSITION FOR LABELLING A PROTEIN, METHOD FOR LABELLING A PROTEIN, AND METHOD FOR DETECTING A PROTEIN OR10J3, NR1H3, NR1H2 MAPT 3586/4885KDM4E 2522/4885RAB9A 1621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.