Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198081 | 1.00 | TDP1 (0.39) | TDP1ALDH1A1GAALMNAMAPT | |
| SCHEMBL906419 | 0.88 | TDP1 (0.44) | TDP1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL874774 | 0.88 | TDP1 (0.44) | TDP1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL29359044 | 0.85 | TDP1 (0.47) | TDP1ALDH1A1GAALMNAMAPT | |
| SCHEMBL5933992 | 0.85 | TDP1 (0.47) | TDP1ALDH1A1GAALMNAMAPT | |
| SCHEMBL13186231 | 0.82 | TDP1 (0.44) | TDP1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL20451 | 0.78 | TDP1 (0.53) | TDP1ALDH1A1GAALMNAKMT2A | |
| SCHEMBL676763 | 0.78 | TDP1 (0.53) | TDP1ALDH1A1GAALMNAKMT2A | |
| SCHEMBL29608839 | 0.78 | TDP1 (0.53) | TDP1ALDH1A1GAALMNAKMT2A | |
| SCHEMBL28267478 | 0.78 | TDP1 (0.64) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000062792-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING PESTS | INSECT BIOTECHNOLOGY, INC. (US) | 2000-10-26 | — | — | WO | claimed |
| US-6593299-B1 | Applying to a pest-inhabited locus of the geographical area the pesticidal peptide Tyr-Asp-Pro-Ala-Phe and applying a pest attractant and in the proximity of the pesticidal composition such that pests are attracted to it | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2003-07-15 | — | — | US | disclosed |
| WO-2000062792-A2 | COMPOSITIONS AND METHODS FOR CONTROLLING PESTS | INSECT BIOTECHNOLOGY, INC. (US) | 2000-10-26 | — | — | WO | disclosed |