Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.75 |
| ▸ | F2 | P00734 | 6/20 | 0.74 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6954719 | 0.99 | F10 (0.77) | F10KCNH2F2PRSS1 | |
| Hydrochloric Acid SCHEMBL6961562 | 0.93 | F10 (0.78) | F10KCNH2F2PRSS1 | |
| SCHEMBL8800030 | 0.92 | F10 (0.81) | F10KCNH2F2PRSS1 | |
| SCHEMBL6956447 | 0.92 | F10 (0.81) | F10KCNH2F2PRSS1 | |
| SCHEMBL6158628 | 0.90 | F10 (0.81) | F10KCNH2F2PRSS1 | |
| SCHEMBL6960754 | 0.90 | F10 (0.78) | F10KCNH2F2PRSS1 | |
| Hydrochloric Acid SCHEMBL6156677 | 0.89 | F10 (0.80) | F10KCNH2F2PRSS1 | |
| SCHEMBL6156620 | 0.89 | F10 (0.83) | F10KCNH2F2PRSS1 | |
| Hydrochloric Acid SCHEMBL6953172 | 0.88 | F10 (0.82) | F10KCNH2F2PRSS1 | |
| SCHEMBL6954191 | 0.88 | F10 (0.76) | F10KCNH2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043020-A1 | MEDICINAL COMPOSITION FOR PERCUTANEOUS ADMINISTRATION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-10-11 | — | — | EP | claimed |
| EP-0966973-A1 | SORBEFACIENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-12-29 | — | — | EP | claimed |
| EP-0953359-A1 | PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-03 | — | — | EP | claimed |
| US-6596754-B1 | Drug for hypercytokinemia, liver diseases, and syndromes caused by the aggravation of sepsis, containing an anti-thrombin agent and/or a thrombin production inhibitor as an active ingredient. The present invention is applicable to | DAIICHI PHARMACEUTICALS CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-1110556-A1 | PREVENTIVES/REMEDIES FOR MULTIPLE ORGAN FAILURE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-1043020-A1 | MEDICINAL COMPOSITION FOR PERCUTANEOUS ADMINISTRATION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0966973-A1 | SORBEFACIENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-12-29 | — | — | EP | disclosed |
| EP-0953359-A1 | PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-03 | — | — | EP | disclosed |