SCHEMBL7198792

SCHEMBL7198792

N#CSCCSc1nc2ccccc2s1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.76
CYP2D6 P10635 3/20 0.76
CYP2C19 P33261 3/20 0.63
CYP3A4 P08684 2/20 0.63
CYP2C9 P11712 1/20 0.63
STAT6 P42226 1/20 0.63
MAPK1 P28482 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
HIF1A Q16665 1/20 0.61
HTR1A P08908 1/20 0.58
HTR2A P28223 1/20 0.58
HTR7 P34969 1/20 0.58
ALDH1A1 P00352 8/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
HSD17B10 Q99714 4/20 0.57
HPGD P15428 4/20 0.57
POLB P06746 3/20 0.57
TSHR P16473 1/20 0.57
IDO1 P14902 1/20 0.56
KDM4E B2RXH2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837665 0.87 CYP1A2 (1.00) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL29352673 0.86 CYP1A2 (0.73) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL54175 0.86 CYP1A2 (0.73) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL8887013 0.86 CYP1A2 (0.73) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
Dimethylamine SCHEMBL8652976 0.84 CYP1A2 (0.65) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL11848946 0.83 CYP1A2 (0.73) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
Thiocyanic Acid SCHEMBL8734334 0.82 CYP1A2 (0.67) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL11115177 0.81 CYP1A2 (0.69) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL10358245 0.80 CYP1A2 (0.67) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
2-Mercaptobenzothiazole SCHEMBL8153954 0.79 CYP1A2 (0.61) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110036056-B Quaternary cationic polymers 埃科莱布美国股份有限公司 2022-09-13 CN disclosed
CN-110117464-B Novel polysiloxane-based fouling control coating systems 汉伯公司 2022-02-18 CN disclosed
US-6586369-B1 Agriculture BASF AKTIENGESELLSCHAFT (DE) 2003-07-01 US disclosed
CN-1143361-A Phenylacetic acid derivatives, their preparation and intermediates, and compositions containing them BASF AG (DE) 1997-02-19 CN disclosed
EP-0604511-B1 SYNERGISTIC COMBINATIONS OF 2-(THIOCYANOMETHYLTHIO)-BENZOTHIAZOLE WITH HEXAHYDRO-1,3,5-TRIS(2-HYDROXYETHYL)-S-TRIAZINE IN CONTROLLING FUNGAL AND BACTERIAL GROWTH IN AQUEOUS FLUIDS BUCKMAN LABOR INC (US) 1996-11-27 EP disclosed
EP-0604511-A1 SYNERGISTIC COMBINATIONS OF 2-(THIOCYANOMETHYLTHIO)-BENZOTHIAZOLE WITH HEXAHYDRO-1,3,5-TRIS(2-HYDROXYETHYL)-S-TRIAZINE IN CONTROLLING FUNGAL AND BACTERIAL GROWTH IN AQUEOUS FLUIDS. BUCKMAN LABOR INC (US) 1994-07-06 EP disclosed
WO-1993004584-A1 SYNERGISTIC COMBINATIONS OF 2-(THIOCYANOMETHYLTHIO)-BENZOTHIAZOLE WITH HEXAHYDRO-1,3,5-TRIS(2-HYDROXYETHYL)-S-TRIAZINE IN CONTROLLING FUNGAL AND BACTERIAL GROWTH IN AQUEOUS FLUIDS BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1993-03-18 WO disclosed
US-4983618-A Tribromophenol, microbiological growth control, synergistic BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1991-01-08 US disclosed
US-4898895-A Antifouling pain having a polyacrylate component with pendent silyl or siloxane groups NIPPON OIL AND FATS CO., LTD. (JP) 1990-02-06 US disclosed