Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE11A | Q9HCR9 | 5/20 | 0.44 |
| ▸ | BCDIN3D | Q7Z5W3 | 4/20 | 0.43 |
| ▸ | PDE5A | O76074 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329237 | 0.92 | BCDIN3D (0.46) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6706955 | 0.90 | PDE11A (0.44) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6706993 | 0.90 | PDE11A (0.44) | PDE11ABCDIN3DPDE5A | |
| Dimethylamine SCHEMBL2325793 | 0.89 | BCDIN3D (0.42) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6706949 | 0.89 | PDE11A (0.43) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6706970 | 0.89 | PDE11A (0.43) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6707009 | 0.89 | PDE11A (0.43) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6707587 | 0.88 | PDE11A (0.43) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6712268 | 0.88 | PDE11A (0.43) | PDE11ABCDIN3DPDE5A | |
| SCHEMBL6753661 | 0.88 | PDE5A (0.43) | PDE11ABCDIN3DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355649-A2 | PHARMACEUTICAL FORMULATION CONTAINING PYRAZOLO 4,3-D]PYRIMIDINE AND NITRATES OR THIENOPYRIMIDINES AND NITRATES | MERCK PATENT GmbH (DE) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002060449-A2 | PHARMACEUTICAL FORMULATION CONTAINING PYRAZOLO[4,3-D]PYRIMIDINE AND NITRATES OR THIENOPYRIMIDINES AND NITRATES | MERCK PATENT GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |