Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1360877 | 0.84 | BLM (0.38) | KDM4ESMN1; SMN2TDP1BLMPMP22 | |
| SCHEMBL2131480 | 0.80 | BLM (0.47) | KDM4ESMN1; SMN2L3MBTL1TDP1BLM | |
| SCHEMBL15133338 | 0.75 | — | — | |
| SCHEMBL14385983 | 0.74 | BLM (0.42) | BLMPMP22HSD17B10 | |
| SCHEMBL6552512 | 0.74 | BLM (0.42) | KDM4ESMN1; SMN2TDP1BLMPMP22 | |
| SCHEMBL7193670 | 0.74 | MVD (0.33) | KMT2AMEN1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7708142 | 0.73 | TDP1 (0.36) | SMN1; SMN2TDP1 | |
| SCHEMBL20600359 | 0.72 | BLM (0.47) | KDM4ETDP1BLMPMP22HSD17B10 | |
| SCHEMBL1081018 | 0.71 | EPOR (0.32) | SMN1; SMN2TDP1 | |
| SCHEMBL1057046 | 0.71 | EPOR (0.32) | SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6590120-B1 | Reacting alkali or earth alkali metal salt of maleic acid with N-substituted diethanolamine, in which two ethanol groups of diethanolamine react while substituent is unreactive with maleic acid salt | KEMIRA CHEMICALS OY (FI) | 2003-07-08 | — | — | US | claimed |
| US-6590120-B1 | Reacting alkali or earth alkali metal salt of maleic acid with N-substituted diethanolamine, in which two ethanol groups of diethanolamine react while substituent is unreactive with maleic acid salt | KEMIRA CHEMICALS OY (FI) | 2003-07-08 | — | — | US | disclosed |