Cyclohexane

Cyclohexane

SCHEMBL7199629

C1CCCCC1.O=C(O)C12C=CC(C(=O)O)(C=C1)C2

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.32
AKR1C1 Q04828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10972957 0.80 CYP2C19 (0.41) CYP2C19AKR1C1
SCHEMBL2361293 0.77 AKR1C1 (0.39) CYP2C19AKR1C1
SCHEMBL1517959 0.75 FFAR3 (0.38) AKR1C1
Cyclohexane SCHEMBL1079006 0.65 FFAR3 (0.41) CYP2C19AKR1C1
Cyclohexane SCHEMBL27575916 0.61 CA1 (0.50) AKR1C1
Cyclohexane SCHEMBL9754177 0.60 CA1 (0.62) CYP2C19
Bicarbonate SCHEMBL934383 0.60 CA1 (0.62) CYP2C19
Bicarbonate SCHEMBL7521496 0.60 CA1 (0.62) CYP2C19
Cyclohexane SCHEMBL168638 0.60 CA1 (0.62) CYP2C19
Cyclohexane SCHEMBL8160484 0.60 CA1 (0.62) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277909-B1 MELT PROCESSABLE POLYMER COMPOSITION COMPRISING THERMOPLASTIC POLYMER, THERMOTROPIC LIQUID CRYSTALLINE POLYMER, REINFORCING FIBER; WHEREIN FIRST AND SECOND POLYMERS HAVE OVERLAPPING MELT PROCESSING RANGE AND ARE IMMISCIBLE EASTMAN CHEMICAL COMPANY 2001-08-21 US claimed
EP-1023362-A1 FIBER REINFORCED RESINS WITH IMPROVED PHYSICAL PROPERTIES AND PROCESS FOR PRODUCING SAME EASTMAN CHEMICAL COMPANY (US) 2000-08-02 EP claimed
US-6051644-A FIRST POLYESTER OF COPOLYESTER AND SECOND THERMOTROPIC LIQUID CRYSTAL POLYMER; WHERE POLYMERS HAVE OVERLAPPING MELT PROCESSING RANGE AND SECOND IS AT LEAST PARTLY IMMISCIBLE WITH THE FIRST; LESSENS FIBER LENGTH REDUCTION DUE TO SHEAR EASTMAN CHEMICAL COMPANY (US) 2000-04-18 US claimed
WO-1999019387-A1 FIBER REINFORCED RESINS WITH IMPROVED PHYSICAL PROPERTIES AND PROCESS FOR PRODUCING SAME EASTMAN CHEMICAL COMPANY (US) 1999-04-22 WO claimed
EP-1023362-B1 FIBER REINFORCED RESINS WITH IMPROVED PHYSICAL PROPERTIES AND PROCESS FOR PRODUCING SAME EASTMAN CHEM CO (US) 2003-02-12 EP disclosed
US-6277909-B1 MELT PROCESSABLE POLYMER COMPOSITION COMPRISING THERMOPLASTIC POLYMER, THERMOTROPIC LIQUID CRYSTALLINE POLYMER, REINFORCING FIBER; WHEREIN FIRST AND SECOND POLYMERS HAVE OVERLAPPING MELT PROCESSING RANGE AND ARE IMMISCIBLE EASTMAN CHEMICAL COMPANY 2001-08-21 US disclosed
EP-1023362-A1 FIBER REINFORCED RESINS WITH IMPROVED PHYSICAL PROPERTIES AND PROCESS FOR PRODUCING SAME EASTMAN CHEMICAL COMPANY (US) 2000-08-02 EP disclosed
US-6051644-A FIRST POLYESTER OF COPOLYESTER AND SECOND THERMOTROPIC LIQUID CRYSTAL POLYMER; WHERE POLYMERS HAVE OVERLAPPING MELT PROCESSING RANGE AND SECOND IS AT LEAST PARTLY IMMISCIBLE WITH THE FIRST; LESSENS FIBER LENGTH REDUCTION DUE TO SHEAR EASTMAN CHEMICAL COMPANY (US) 2000-04-18 US disclosed
WO-1999019387-A1 FIBER REINFORCED RESINS WITH IMPROVED PHYSICAL PROPERTIES AND PROCESS FOR PRODUCING SAME EASTMAN CHEMICAL COMPANY (US) 1999-04-22 WO disclosed