Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 13/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074175 | 0.87 | ADRB3 (0.86) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7130105 | 0.83 | ADRB3 (0.70) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7130113 | 0.83 | ADRB3 (0.70) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6074734 | 0.79 | ADRB3 (1.00) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7204658 | 0.79 | ADRB3 (0.55) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7164934 | 0.78 | ADRB3 (0.67) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7167667 | 0.78 | ADRB3 (0.75) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7166129 | 0.77 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7163827 | 0.77 | ADRB3 (0.76) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7133544 | 0.76 | ADRB3 (0.82) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301482-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006232-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |