Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Dimethylformamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL21461977 | 0.95 | — | — | |
| Dimethylformamide SCHEMBL2280000 | 0.95 | — | — | |
| Dimethylformamide SCHEMBL10141201 | 0.95 | — | — | |
| Dimethylformamide SCHEMBL1332179 | 0.95 | — | — | |
| Dimethylformamide SCHEMBL5 | 0.95 | — | — | |
| Dimethylformamide SCHEMBL1927321 | 0.95 | TSHR (1.00) | — | |
| Dimethylformamide SCHEMBL15142512 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL22749119 | 0.90 | — | — | |
| Dimethylformamide SCHEMBL20475061 | 0.90 | — | — | |
| Dimethylformamide SCHEMBL21436169 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851549-B | 5-hydrogen-benzo [ b ] carbazole and related derivatives and synthetic method thereof | 西安欧得光电材料有限公司 | 2022-03-29 | — | — | CN | claimed |
| WO-2023221234-A1 | IN VITRO SCREENING METHOD FOR COVALENT INHIBITOR AND USE THEREOF | 清华大学 | 2023-11-23 | — | — | WO | disclosed |
| CN-109851549-B | 5-hydrogen-benzo [ b ] carbazole and related derivatives and synthetic method thereof | 西安欧得光电材料有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-110183491-A | A method of recycling by-product p-methyl benzenesulfonic acid magnesium synthesis tenofovir | 黄石福尔泰医药科技有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-109476641-A | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-101381379-A | Kinase inhibitor phosphonate conjugates | GILEAD SCIENCES INC (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-1819832-A | Kinase inhibitory phosphonate analogs | GILEAD SCIENCES INC (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1780631-A | anticancer phosphonate analogs | GILEAD SCIENCES INC (US) | 2006-05-31 | — | — | CN | disclosed |
| US-6593319-B1 | Novel 17,20-dihydrofusidic acid derivatives are used in pharmaceutical compositions for the treatment of infections, in particular in topical compositions for the treatment of skin or eye infections. | LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) | 2003-07-15 | — | — | US | disclosed |
| EP-1232173-B1 | FUSIDIC ACID DERIVATIVES | LEO PHARM PROD LTD (DK) | 2003-05-28 | — | — | EP | disclosed |
| EP-1232173-A1 | FUSIDIC ACID DERIVATIVES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001029061-A1 | NOVEL FUSIDIC ACID DERIVATIVES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-04-26 | — | — | WO | disclosed |
| CN-87102944-A | Ergolene derivatives, pharmaceutical compositions and process for preparing them | — | 1987-11-25 | — | — | CN | disclosed |
| US-4150047-A | AMIDE SOLVENT, LEWIS ACID | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1979-04-17 | — | — | US | disclosed |