Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 9/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.46 |
| ▸ | SYK | P43405 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077567 | 0.85 | PDGFRB (0.52) | PDGFRBPDGFRASYKEGFRFGFR1 | |
| SCHEMBL7079355 | 0.79 | PDGFRB (0.51) | PDGFRBPDGFRASYKLMNAUSP2 | |
| SCHEMBL7081452 | 0.77 | SYK (0.50) | PDGFRBPDGFRASYKLMNAMAPK1 | |
| SCHEMBL7082077 | 0.77 | SYK (0.52) | PDGFRBPDGFRASYKLMNAMAPK1 | |
| SCHEMBL7081454 | 0.75 | SYK (0.53) | SYKEGFRFGFR1LMNAMAPK1 | |
| SCHEMBL7077410 | 0.75 | SYK (0.52) | SYKLMNAMAPK1KDRKDM4E | |
| SCHEMBL7083647 | 0.75 | SYK (0.48) | PDGFRBPDGFRASYKLMNAMAPK1 | |
| SCHEMBL7078467 | 0.75 | PDGFRB (0.56) | PDGFRBPDGFRASYKLMNAUSP2 | |
| SCHEMBL7077905 | 0.73 | PDGFRB (0.67) | PDGFRBPDGFRALMNAUSP2HSD17B10 | |
| SCHEMBL7081409 | 0.73 | SYK (0.46) | PDGFRBPDGFRASYKLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608058-B2 | Therapeutic composition for hepatitis B, hepatitis C, or acquired immune deficiency syndrome | DONG WHA PHARM. IND. CO., LTD. (KR) | 2003-08-19 | — | — | US | disclosed |