Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962419 | 0.80 | HIF1A (0.49) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL490816 | 0.72 | HIF1A (0.62) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL17156491 | 0.70 | HIF1A (0.66) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL890821 | 0.70 | HIF1A (0.66) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL891349 | 0.70 | HIF1A (0.66) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL891143 | 0.70 | HIF1A (0.66) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL17156498 | 0.70 | HIF1A (0.60) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL21690209 | 0.70 | HIF1A (0.43) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL891270 | 0.66 | HIF1A (0.53) | HIF1AEPAS1MAPTHTTGPR84 | |
| SCHEMBL8610814 | 0.64 | HIF1A (0.53) | HIF1AEPAS1MAPTHTTGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596902-B2 | Useful for insecticides and the control of acarid pests; chemical intermediates in the preparation of arylpyrrole compounds such as chlorfenapyr | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | disclosed |
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AMERICAN CYANAMID COMPANY | 2002-04-25 | — | — | US | disclosed |
| US-6320059-B1 | REACTING N-(1-CHLORO-1-(PERFLUOROALKYL)METHYL)ARYLIMIDOYL CHLORIDE COMPOUND WITH DIENEOPHILE COMPOUND OR SUBSTITUTED HALOETHANE COMPOUND, AND BASE, IN PRESENCE OF SOLVENT | AMERICAN CYANAMID COMPANY | 2001-11-20 | — | — | US | disclosed |
| US-6133455-A | INSECTICIDAL AND ACARICIDAL AGENTS; PREPARED FROM N-(ARYLMETHYLENE)-1-CHLORO-1-(PERFLUOROALKYL) METHYLAMINE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-5965773-A | A CHEMICAL INTERMEDIATE FOR FORMING A PESTICIDE TO CONTROL INSECT AND ACARID PESTS | AMERICAN CYANAMID COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| US-5817834-A | FROM (PERFLUOROALKYLMETHYL)ARYLIMIDOLYL CHLORIDE COMPOUNDS;INSECTICIDES, MITICIDES | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049338-A1 | Process for the preparation of 2-aryl-5- (perfluoro-alkyl) pyrrole compounds from N-[1-chloro-1-(perfluoroalkyl) methyl] arylimidoyl chloride compounds | AFF1, AFF4, AFF2 | HIF1A 4838/4885EPAS1 2552/4885MAPT 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.