Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771361 | 0.90 | AR (1.00) | AR | |
| SCHEMBL1771931 | 0.84 | AR (1.00) | AR | |
| SCHEMBL1771515 | 0.83 | AR (0.81) | AR | |
| SCHEMBL1770781 | 0.81 | AR (1.00) | AR | |
| SCHEMBL1772115 | 0.81 | AR (0.79) | AR | |
| SCHEMBL1773651 | 0.81 | AR (0.74) | AR | |
| SCHEMBL1771015 | 0.81 | AR (0.73) | AR | |
| SCHEMBL1771005 | 0.80 | AR (1.00) | AR | |
| SCHEMBL1771418 | 0.80 | AR (0.75) | AR | |
| SCHEMBL1770804 | 0.80 | AR (0.76) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566372-B1 | Useful in female hormone replacement therapy and as modulators of fertility; therapy of dysfunctional uterine bleeding, dysmenorrhea, endometriosis, leiomyomas (uterine fibroids), hot flashes, mood disorders, meningiomas, cancer | LIGAND PHARMACEUTICALS INCORPORATED | 2003-05-20 | — | — | US | disclosed |