SCHEMBL72015

SCHEMBL72015

CC(=O)NN=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29183849 0.76
SCHEMBL137729 0.71
SCHEMBL3359802 0.69
SCHEMBL11437805 0.69
SCHEMBL131896 0.69
SCHEMBL2616122 0.69
SCHEMBL343538 0.69
SCHEMBL5685779 0.69
SCHEMBL1686793 0.69
SCHEMBL345509 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170368235-A1 PHARMACEUTICAL COMPOSITIONS AND DEVICE METHODS FOR TREATMENT OF PROLIFERATIVE DISEASES DINH THOMAS Q (US) 2017-12-28 US claimed
US-20160008518-A1 PHARMACEUTICAL COMPOSITIONS AND DEVICES FOR TREATMENT OF PROLIFERATIVE DISEASES DINH THOMAS Q (US) 2016-01-14 US claimed
EP-0759066-B1 PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF DEGUSSA (DE) 2001-06-27 EP claimed
US-20170368235-A1 PHARMACEUTICAL COMPOSITIONS AND DEVICE METHODS FOR TREATMENT OF PROLIFERATIVE DISEASES DINH THOMAS Q (US) 2017-12-28 US disclosed
US-20160008518-A1 PHARMACEUTICAL COMPOSITIONS AND DEVICES FOR TREATMENT OF PROLIFERATIVE DISEASES DINH THOMAS Q (US) 2016-01-14 US disclosed
EP-2966078-A2 Inhibitors of histone deacetylase MethylGene Inc. (CA) 2016-01-13 EP disclosed
US-20140309174-A1 HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER EISAI CO., LTD (JP) 2014-10-16 US disclosed
EP-2767595-A1 Detection method for characterising the anatomical origin of a cell Clinical Genomics Pty Ltd (AU) 2014-08-20 EP disclosed
US-8633224-B2 Hemiasterlin derivatives and uses thereof in the treatment of cancer EISAI CO., LTD. (JP) 2014-01-21 US disclosed
US-20120329987-A1 Metal Abstraction Peptide (MAP) Tag and Associated Methods UNIVERSITY OF KANSAS (US) 2012-12-27 US disclosed
US-20120309938-A1 HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER EISAI CO., LTD. (JP) 2012-12-06 US disclosed
WO-2005030794-A2 HEMIASTERLIN DERIVATIVES AND USES THEREOF EISAI CO. LTD. (JP) 2005-04-07 WO disclosed
EP-1490054-A2 HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER Eisai Co., Ltd (JP) 2004-12-29 EP disclosed
US-20040229819-A1 Hemiasterlin derivatives and uses thereof EISAI CO., LTD. (JP) 2004-11-18 US disclosed
WO-2003082268-A2 HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER EISAI CO. LTD (JP) 2003-10-09 WO disclosed
EP-0759066-B1 PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF DEGUSSA (DE) 2001-06-27 EP disclosed
EP-0759066-A1 PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF Degussa Aktiengesellschaft (DE) 1997-02-26 EP disclosed
WO-1995030740-A1 PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF DEGUSSA AKTIENGESELLSCHAFT (DE) 1995-11-16 WO disclosed
US-4659503-A Pyridylthiophenes Merck Patent Gesellschaft Mit Beschrankter Huftung (DE) 1987-04-21 US disclosed
EP-0146862-A2 Pyridyl thiophenes MERCK PATENT GmbH (DE) 1985-07-03 EP disclosed