Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.70 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL786272 | 1.00 | CA4 (0.70) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL785519 | 1.00 | CA4 (0.70) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL28387560 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL7620105 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL3416799 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL234978 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL7981840 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL2722478 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL169342 | 0.94 | — | — | |
| Oxalic Acid SCHEMBL191688 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6589751-B2 | Antibody specific for homocystamide adducts, such as those formed by dehydrating homocysteine to homocysteine thiolactone and reaction this with a carrier such as low density lipoprotein (LDL) to form homocystamide-LDL adduct | MCW RESEARCH FOUNDATION | 2003-07-08 | — | — | US | disclosed |
| US-20020015968-A1 | IMMUNOLOGICAL DETECTION OF THE HOMOCYSTAMIDE ADDUCT AND A THIOLACTONE IMMUNOASSAY FOR ENDOGENEOUS HOMOCYSTEINE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-02-07 | — | — | US | disclosed |