Isoproturon

Isoproturon

SCHEMBL7202232

CC(C)c1ccc(NC(=O)N(C)C)cc1.CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.79
TSHR P16473 2/20 0.57
EPHX1 P07099 2/20 0.51
EPHX2 P34913 2/20 0.51
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PANK3 Q9H999 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
CHRM1 P11229 1/20 0.50
SLC6A2 P23975 1/20 0.50
PDE4A P27815 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dcmu SCHEMBL7279 0.89 APEX1 (1.00) APEX1TSHREPHX1EPHX2MAPT
Dcmu SCHEMBL1352353 0.89 APEX1 (1.00) APEX1TSHREPHX1EPHX2MAPT
Dcmu SCHEMBL29349863 0.89 APEX1 (1.00) APEX1TSHREPHX1EPHX2MAPT
Dcmu SCHEMBL28379561 0.88 APEX1 (0.96) APEX1TSHREPHX1EPHX2MAPT
Dcmu SCHEMBL20723673 0.88 APEX1 (0.96) APEX1TSHREPHX1EPHX2MAPT
Dcmu SCHEMBL10491599 0.88 APEX1 (0.96) APEX1TSHREPHX1EPHX2MAPT
Dcmu SCHEMBL28964105 0.88 APEX1 (0.96) APEX1TSHREPHX1EPHX2MAPT
Dcmu SCHEMBL20723892 0.88 APEX1 (0.96) APEX1TSHREPHX1EPHX2MAPT
Isoproturon SCHEMBL62200 0.87 TSHR (0.67) APEX1TSHRSMN1; SMN2ALDH1A1HPGD
Isoproturon SCHEMBL8518619 0.87 TSHR (0.67) APEX1TSHRSMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003055959-A1 LOW-DUST SOLID FUEL PREPARATIONS BAYER CHEMICALS AG (DE) 2003-07-10 WO disclosed