Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.58 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305274 | 0.98 | ELANE (0.56) | ELANEPPARAZDHHC2FAAHATM | |
| SCHEMBL6257018 | 0.90 | ELANE (0.71) | ELANEPPARAZDHHC2ATML3MBTL1 | |
| SCHEMBL17028379 | 0.87 | ELANE (0.62) | ELANE | |
| SCHEMBL17028385 | 0.86 | ELANE (0.51) | ELANEL3MBTL1 | |
| SCHEMBL28650223 | 0.85 | ZDHHC2 (0.44) | ELANEZDHHC2FAAH | |
| SCHEMBL20853943 | 0.84 | ELANE (0.44) | ELANEPPARAZDHHC2FAAHATM | |
| SCHEMBL19050193 | 0.83 | ELANE (0.70) | ELANEPPARA | |
| SCHEMBL20853911 | 0.83 | ZDHHC2 (0.47) | ELANEPPARAZDHHC2FAAH | |
| SCHEMBL131278 | 0.82 | ELANE (0.51) | ELANEPPARAATML3MBTL1 | |
| SCHEMBL19105286 | 0.82 | ZDHHC2 (0.43) | ELANEZDHHC2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030882-A9 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2003-02-20 | — | — | WO | claimed |
| CN-1073087-C | Process for producing acyloxybenzenesulfonic acid or salt thereof | KAO CORP (JP) | 2001-10-17 | — | — | CN | disclosed |