Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.56 |
| ▸ | KLK1 | P06870 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421240 | 0.86 | F10 (0.55) | F10KLK1KMT2AHRH1HRH4 | |
| SCHEMBL5196283 | 0.85 | F10 (0.71) | F10KLK1 | |
| SCHEMBL6735877 | 0.84 | F10 (0.54) | F10KLK1ALDH1A1HRH1HRH4 | |
| SCHEMBL6729216 | 0.83 | F10 (0.55) | F10KLK1ALDH1A1HRH1HRH4 | |
| SCHEMBL6728636 | 0.83 | F10 (0.58) | F10KLK1ALDH1A1HRH1HRH4 | |
| SCHEMBL6730994 | 0.83 | F10 (0.61) | F10KLK1OPRM1 | |
| SCHEMBL6421720 | 0.82 | F10 (0.53) | F10KLK1HRH1HRH4HRH3 | |
| SCHEMBL6781543 | 0.82 | F10 (0.61) | F10KLK1ALDH1A1 | |
| SCHEMBL6735874 | 0.82 | F10 (0.54) | F10KLK1ALDH1A1HRH1HRH4 | |
| SCHEMBL6730422 | 0.82 | F10 (0.74) | F10KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158120-A1 | Combination product comprising melagatran and a factor xa inhibitor | ASTRZENECA AB (SE) | 2003-08-21 | — | — | US | disclosed |