Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.76 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.76 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975607 | 0.89 | ESR2 (0.76) | ESR1ESR2CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL29366409 | 0.89 | ESR2 (0.76) | ESR1ESR2CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL15913830 | 0.87 | ESR2 (1.00) | ESR1ESR2CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL11049466 | 0.86 | ESR1 (0.56) | ESR1ESR2CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL4360502 | 0.86 | ESR1 (0.63) | ESR1ESR2CYP19A1ALDH1A1CYP3A4 | |
| SCHEMBL2968481 | 0.84 | ESR1 (0.72) | ESR1ESR2CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL11047047 | 0.84 | ESR1 (0.52) | ESR1ESR2CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL4364022 | 0.82 | ESR2 (0.83) | ESR1ESR2CYP19A1ADORA3MAOB | |
| SCHEMBL27517082 | 0.82 | ESR2 (0.83) | ESR1ESR2CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL4361595 | 0.81 | ESR2 (0.82) | ESR1ESR2CYP19A1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617293-A | Flavonoid phosphate salts of aminoglycoside antibiotics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | claimed |
| EP-1286706-A2 | GAMMA IRRADIATION OF PROTEIN-BASED PHARMACEUTICAL PRODUCTS | The American National Red Cross (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087357-A2 | GAMMA IRRADIATION OF PROTEIN-BASED PHARMACEUTICAL PRODUCTS | THE AMERICAN NATIONAL RED CROSS (US) | 2001-11-22 | — | — | WO | disclosed |
| US-4617293-A | Flavonoid phosphate salts of aminoglycoside antibiotics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1986-10-14 | — | — | US | disclosed |
| EP-0065123-B1 | HARDLY SOLUBLE SALTS OF AMINOGLYCOSIDE ANTIBIOTICS | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| EP-0065123-A1 | Hardly soluble salts of aminoglycoside antibiotics | MERCK PATENT GmbH (DE) | 1982-11-24 | — | — | EP | disclosed |