Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197818 | 0.92 | KDM4E (0.48) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL12765886 | 0.92 | KDM4E (0.48) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL26534796 | 0.89 | TYMP (0.40) | KDM4ETYMPTAS1R3TAS1R1HPGD | |
| SCHEMBL26533944 | 0.89 | TYMP (0.40) | KDM4ETYMPTAS1R3TAS1R1HPGD | |
| SCHEMBL26347716 | 0.88 | TYMP (0.40) | KDM4ETYMPTAS1R3TAS1R1HPGD | |
| SCHEMBL21901418 | 0.88 | KDM4E (0.52) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL17222397 | 0.87 | KDM4E (0.47) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL23425410 | 0.87 | KDM4E (0.46) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL3820892 | 0.87 | KDM4E (0.56) | KDM4ETYMPTAS1R3TAS1R1POLA1 | |
| SCHEMBL10533862 | 0.86 | KDM4E (0.41) | KDM4ETYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203356-A1 | RNase L activator-antisense complexes | THE CLEVELAND CLINIC FOUNDATION (US) | 2003-10-30 | — | — | US | disclosed |
| US-6214805-B1 | GENES, GENE SIGNALS, GENOMES RNA STRANDS AND RESPIRATORY SYNCYTIAL VIRUS WITH PROMOTERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-04-10 | — | — | US | disclosed |
| EP-1007655-A1 | RNASE L ACTIVATORS AND ANTISENSE OLIGONUCLEOTIDES EFFECTIVE TO TREAT RSV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5998602-A | RNase L activators and antisense oligonucleotides effective to treat RSV infections | THE CLEVELAND CLINIC FOUINDATION AND GOVERNMENT (US) | 1999-12-07 | — | — | US | disclosed |