SCHEMBL7202392 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CYP3A4	P08684	2/20	0.35

▸	MEN1	O00255	1/20	0.35

▸	ALOX15	P16050	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	ALDH1A1	P00352	2/20	0.33

▸	USP2	O75604	2/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	LMNA	P02545	1/20	0.30

▸	TSHR	P16473	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL93735	0.89	TSHR (0.44)	CYP3A4ALDH1A1USP2MAPTHPGD
Alcohol SCHEMBL28225509	0.73	TSHR (0.50)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL2326413	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL104256	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL131602	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL9220719	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL2998034	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL399787	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL2936701	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1
SCHEMBL1904498	0.73	TSHR (0.52)	CYP3A4MEN1ALOX15KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2002041827-A9	METHODS EMPLOYING AND COMPOSITIONS CONTAINING DEFINED OXIDIZED PHOSPHOLIPIDS FOR PREVENTION AND TREATMENT OF ATHEROSCLEROSIS	VASCULAR BIOGENICS LTD (IL)	2003-05-30	—	—	WO	disclosed